The Bioclean Project is organized in 5 distinct work packages (WPs):
WP1: Surfaces (Leader P&G)
Soil removal of Complex organic Soil Via Surface Modification
- Surface Modification to prevent or loosen adhesion soil
- Develop Structure-Functional property relationship models to identify best surface modification approaches
- Study Microbial response to surface modification strategies
- Attachment and detachment of soils on modified surfaces under flow
- Chemical modification of natural polymers for malodour reduction
WP2: Mechanisms (Leader CSGI)
Disruption of Microbial Cell wall
- Develop mechanistic understanding into disruption of cell envelope and biochemical processes inside cytoplasm
- Understanding oxidative pathways inside cells
Weaken Soil – Substrate interaction
- Reduce Complex Organic Soils internal network
- Impact of flow-through porous substrates (sponge, fabric) on Complex Organic Soil
- Impact of mechanical force on oral biofilm
WP3: Methods/Models/Molecules (Leader P&G)
- SAXS to measure the kinetics and the mechanism of how actives affect cell morphology
- MRI and 3D Micro CT to visualise flow and diffusion properties within and surrounding biologically-derived soil especially in optically opaque porous substrates like sponge and fabric
- Micromanipulation: Study Adhesive and cohesive forces in biofilm and the factors leading to dislodging the soil from surfaces.
- Synthesis of novel polymers for soil repellency and chemical modification of natural polymers for Malodour Control
WP4: Application (Leader University of Birmingham)
Application of surface modification in industry-relevant environments & substrates, e.g. human, fabric & home, food, marine surfaces.
Design products and technologies that either prevent the adhesion of soils or significantly ease the removal of soils from surfaces with minimum physical attrition.
WP5: Knowledge Transfer and Dissemination (Leader CSGI)
- Ensure effective knowledge transfer internally and externally; create broad based public awareness and understanding in the biofilm management work area via open science plus numerous and different types of dissemination and outreach activities.